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October 31, 2017     The Hinton News
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Tiny Biotechs Get Giant Results In Leukemia Treatment (NAPS)--A revolutionary new treat- ment for relapsed chronic lymphocytic leukemia (CLL) may soon be available. For decades, the only treatment for CLL was toxic chemotherapy that provided limited benefit. However, over the last 20 years, major strides have been made 11 in the quest to develop a new treatment that is both safe and effective, and each new development can be attributed to efforts made by a tiny biotech company. In fact, very recently, a tiny biotech called TG Therapeutics released exciting ~1~~ data concerning an innovative new treat- ment, TG-1101 (ublituximab),for CLLpa- Researchers have discovered a way tients that builds on those past successes, to encourage the body's own im- So, in essence then, TG's success re- mune system to fight offcancer. ally begins decades ago. It was back in 1996 when researchers at a tiny compa- be much more effective due to a tech- ny calle3 Idec Pharmaceuticals discov- nique that enabled TG-1101 to better ered Rit~xan. Rituxan was the first drug engage the immune system to more ef- to harness the immune system to treat fectively kill the cancer cells. leukemias and lymphomas, and all these Alone, TG-1101 is an exciting ad- years later it is still hailed as one of the vance, but the major breakthrough came greatest breakthroughs in the treatment about when TG-110! was combined of cancer, with ibrutinib. "We were excited to see The next breakthrough occurred in if we could create a really potent com- 2010, when another small biotech com- bination that was safe for our patients," paW, Pharmacyclics, developed ibruti- stated Dr. Kolibaba. In TG's first Phase 2 nib. It was referred to as the magic pill clinical trial evaluating the chemother- for CLL. About half the patients who re- apy-free combination, published in the lapsed after chemotherapy and Rituxan prestigious British Journal of Haematol- responded to ibrutinib. Unfortunately, ogy, nearly all patients treated achieved ibrutinib alone was not the answer for great benefit and experienced a major all patients, reduction in their disease. "Ibrutinib has been a great addition A Phase 3 clinical trial for the same to our CLL armamentarium. Howev- combination followed, and confirmed er, we have long believed that ibrutinib the impressive Phase 2 findings. Inves- alone may not be enough, particularly tigators .again found that the addition of for patients with high-risk disease;' said TG-1101 to ibrutinib improved the re- Dr. Kathryn Kolibaba, who is the Asso- sponse rate by more than 70 percent as ciate Chair of the Hematology Research compared to ibrutinib alone. Committee for US Oncology and prac- "These are the first Phase 3 results tices at Compass Oncology in Vancou- showing that we can dramatically in- ver, Washington. crease the remission rate for CLL patients That is why, in 2013, Dr. Kolibaba taking ibrutinib without the addition of and her colleagues at US Oncology part- toxic chemotherapy and is truly a great nered with TG Therapeutics to research advance for patients," stated Dr. Kolibaba. the potential of TG-1101 as a treatment More information about TG Thera- option for CLL. What intrigued them peutics and TG-1101 (ublituximab)can about TG's compound was that it was be found at www.tgtherapeutics.com similar to Rituxan yet it was designed to and www.BCellClinicalTrials.com. Apply Online at www.qualitydriveaway.com or call 574-642-2023 Education Today Survey: Majority Of Working Adults See Higher Education As Route To Greater Career Satisfaction (NAPS)--Americans are thinking more about how to pursue professional development and open doors to more satisfying career options. In fact, accord- ing to a recent University of Phoenix® survey, only 38 .percent of U.S. working adults are very satisfied with their cur- rent professional position, and just 37 'pefce~t;report that they' are ee~y"satt~- ;' [~With their ¢ffrrent'career path. The survey also found that less than half (43 percent) of respondents say they are very satisfied with how their skills and abilities are utilized by their em- ployers, and more than a third (38 per- cent) feel they are undercompensated, A3 a result, many are looking for ways to improve their professional outlOok. One option to help improve career satisfaction and trajectory is to go back to school. The survey found that nearly 65 percent of Americans anticipate their current salary would increase if they were to achieve the next level of educa- tion. Additionall); about 72 percent say this achievement would have an impact on their career satisfaction. ]he obstacle many find, especially working adults, is how to make earning an education a reality. Deciding to pursue more education can be a major decision, but Peter Cohen, president of University of Phoenix, says there are several steps one can take to en- sure they have a fulfilling experience: • First, Cohen recommends determin- ing your professional goals and how higher education might help you achieve them. Whether to upgrade your skills to make yourself a more valuable employee, give yourself the opportunity to take on greater chal- lenges or even pursue an entirely new career, you should think carefully about your goals and make an educa- tional plan that suits them well• Study shows most people would change careers--if they knew how. • Next, consider how you are going to make education fit into the rest of your life. Working adults know well the challenges of balancing the demands of a job, family and other responsibili- ties. 2he good news is that, in addition to flexible in-classroom options, there are a variety, of online and blended learning solutions that can allow you to pursue professional development on your own time. • Finally, don't worry if this seems a bit overwhelming. It can seem like there are too many decisions to make and too little time to figure them out. Colleges and universities have well- trained staff and advisers to help guide you through every step of the process. ':As economic conditions continue to improve and job opportunities mul- tiply, it's no surprise that Americans are taking notice and thinking more about how they can make headway in their careers," said" Cohen. "At University of Phoenix, we are keenly attuned to the workforce trends driving our economy, and we are committed to offering pro- fessional development opportunities that help students meet market needs" For further information about Uni- versity of Phoenix, visit www.phoenix. edu. HUBCAP KICKOFF PARTY Hinton was one of several communities around the state chosen to be a part of the WV Community Development Hub's Community of Achievement Program (HubCAP). Working with Summers County, the City of Hinton, and local citizens, the HubCAP program will empower the local community to achieve a data driven community project. At the kickoff party on November 9th' the attendees will give their feedback on the project they most want to see undertaken. The projects will focus on building redevelopment and business recruitment. The kickoff party will be held November 9th from 5-7:30 p.m, in the Freight Depot (509 Commercial Street)• Registration and networking begins at 5 p.m., while speakers will start around 5:30 p.m.; a roundtable discussion and dinner will follow the speakers. All are welcome and encouraged to come celebrate the past, present, and future achievements of the Hinton area. Please contact Sarah Rogers or Cris Meadows at 304-466-3255 with any questions. • PUBLIC SERVICE ANNOUNCEMENT Drug overdoses have become the leading cause of accidental death in the United States with heroin and other opiates being the largest contributor. If your loved one is struggling with drug abuse of any kind, now is the time to get them the help they need. Learn more about the signs of heroin addiction. If you believe one of your loved ones is abusing drugs, learn how you can make a difference by visiting http:// www.narcononnewliferetreat.org! drug-rehab! Addiction Screenings Narconon can help you take steps to overcome addiction in your family. Call today for free screenings or referrals. 1- 800-431-1754. CFM HOUSE MUSEUM The Campbell-Ftannagan- Murrell House Museum at 422 Summers St., in Historic Downtown Hinton is open each Saturday from I to 4 p.m. for Free Tours. For more information call 304- 445-5769. To me, old age I am, is 15 years older than --Bernard M.-Baruch ..... I I ......... OWN THE PROSECT RENT THE TOOL 9692 Seneca Trail SOuth Faidea WV 24902 (304) 645-7326 = UI I IIII FOR RENT: One Bedroom, Section 8 apts. for the Elderly, Handicapped or Disabled. All utilities included. On site laundry facilities. Office hours M-F, 8-4. Hinton House Apts. 304-466-5299 CIP~2Y~T UMIy Ir CLASSiFiED ADS. ONLY 35¢ ,wo d 12 N Thursday• (The paper Is responsible for only one Incorrect Insertion.) BUSINESS ADS line 12 N Thursday Earl Tupper, of Tupperware fame, is believed to have gotten the design for Tupperware's liquidproof, airtight lids by duplicating the lid of a paint can. watchdog Alerts / Tips & Resources / Free for Everyone Fraud Watch Network Tues. Oct. 31, 2017 Hinton News - 9 I FOR SALEI ? DISH TV 190 CHANNELS plus SAW MILLS from only $4,397.00- Highspeed Internet Only $49.94/mo! MAKE & SAVE MONEY with your Ask about a 3 year price guarantee own bandsaw - Cut lumber any & get Neffiix included for 1 year! demension. In stecl ready to ship~ Call Today 1-800-261-7884 FREE Info/DVD: www.Norwood HN Feb. 23-TFN Sawmills.corn 1-800-578-1363 Ext. 300N HN Aug. 29-TFN Stop Overpaying for your prescriptions! Save up to 93%! Call our licensed Canadian and International pharmacy service to compare prices and get $15.00 off your first prescription and FREE Shipping. 1-800-912-5083. May 17-TFN Hands on the River Massage, Geraldine Gardner, LMT, 3422 Pennsylvania Ave., Charleston, WV. Call (304) 541-9139 for an appointment, HN Oct. ll-TFN Mechanic Wanted, must be able to pass drug test and have valid driver's license. Any questions on this position call us at 304-466-4500. HN Aug. 1-TFN GOT KNEE PAIN? Back Pain? Nurturing couple will provied a Shoulder Pain? Get a pain-relieving stable, secure home, full of brace - little to NO cost to you. •unconditional love for your baby. Medicare Patients Call Health Expenses paid. Call/Text 646-983- Hotline Now! 1-800-758-1595. 1623. Lisa and Brian. HN Feb. 28-TFN HN Oct. 24-TFN Looking for CDL A or B drivers to deliver new trucks all over the US and Canada. Experience preferred. Must have DOT physical and be willing to keep logs. 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( i.¢ 'r How To NEWS ARTICLES General Information and Writing. Tips • The newspaper welcomes news submissions concerning club activities, sports, birthday announcements and anniversaries, engagements and weddings, academic honors, church activities and all community activities. • Everything submitted is subject to editing and all news articles run without charge and run on a "space available" basis. • Either type or legibly print your article, ' using upper and lowercase letters (NOT all caps). If possible, double--space between lines to allow ¢oom for copy editing marks. • The basic elements of a news article are: Who, What, When, Where and Why. Make sure your story includes all five W's. • Write your news article in the third person (he, they, their), not the first person (I, we, our). • Double-check the spelling of names and places mentioned in your story, and make sure the date(s) of your event matches the day(s). • Always include the name and daytime telephone number of a contact person in case there are questions about the news item. E-Mailed Articles • The best way to send an articl 'via the Internet is to include the text of the article in the body of the e-mail and not as an attachment. Text in Word format is acceptable, but the newspaper cannot accept Wordpad, WordPerfect or Publisher files. To be safe, Cut and paste into the e-mail. • Do not send text as a jpg or any other type of graphic file. An accompanying picture should be sent as a high-resolution jpg. • See "How To Get Into Print - Photographs" for more information on submitting photographs. The Hinton News • P O Drawer 1000 Hinton, WV 25951-1000 hintonl000@aol.com